GONADORELIN

240.00 AED — In stock

Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH), the hypothalamic hormone that drives the release of LH (luteinizing hormone) and FSH (follicle-stimulating hormone) from the pituitary. These hormones are essential for regulating fertility, testosterone, and estrogen production in both men and women. It is studied for its role in fertility support, HPG axis regulation, and reproductive optimization in clinical and research settings. (pubmed.ncbi.nlm.nih.gov) ⚗️ Product Features 🧪 Synthetic GnRH peptide for endocrine research 🔬 Stimulates LH and FSH secretion via pituitary activation ⚙️ Supports research into reproductive health, fertility, and hormone regulation ✅ ≥98 % purity verified by HPLC 📄 Batch-specific Certificates of Analysis (COAs) included 💧 Sterile, lyophilized peptide for research applications ⭐ Key Benefits 📈 Supports natural reproductive hormone regulation through LH & FSH stimulation 💡 Promotes fertility and HPG axis balance in men and women ⚖️ May aid in hormonal optimization protocols for testosterone and estrogen research 🔬 Human-Relevant Research Applications 🧠 HPG Axis Modulation Gonadorelin administration in humans has been shown to stimulate pulsatile release of LH and FSH, directly impacting reproductive hormone signaling and supporting fertility research.🔗 https://pubmed.ncbi.nlm.nih.gov/23110338/ Gonadorelin stimulates LH and FSH release in human subjects, demonstrating its utility in reproductive hormone studies. 🧾 Mechanism Summary 📈 Activates the pituitary to release LH and FSH 🔄 Supports gonadal hormone production (testosterone and estrogen) ⚙️ Regulates HPG axis feedback loops in research and clinical models 🔄 Reconstitution & Handling Guidance 1️⃣ Reconstitute using sterile bacteriostatic water2️⃣ Add appropriate volume per research protocol3️⃣ Gently swirl — do not shake4️⃣ Store reconstituted peptide at 4–10 °C5️⃣ Refrigerate unopened vials until use

More All Products

What is GONADORELIN?

Gonadorelin is a synthetic version of natural gonadotropin-releasing hormone (GnRH), a ten amino acid peptide made in the hypothalamus. Its sequence is identical to the human hormone.

GnRH is released in pulses and acts on receptors in the pituitary gland. This prompts the release of luteinising hormone (LH) and follicle-stimulating hormone (FSH), which regulate the testes and ovaries. The timing matters. Pulsed exposure supports this signalling, while continuous exposure can desensitise the pituitary and reduce it. Gonadorelin has a very short half-life of a few minutes.

Also known as: GnRH, LHRH, Gonadotropin-releasing hormone, Luteinising hormone-releasing hormone, Factrel, Lutrepulse

What are peptides?

What the research covers

Gonadorelin has been studied in human clinical research for decades. Studies in the 1980s showed that pulsed, low-dose GnRH could start puberty in men with hypogonadotropic hypogonadism. It has also been studied for ovulation induction and used as a diagnostic test of how well the pituitary works. Laboratory work has compared how gonadorelin and synthetic GnRH agonists bind the GnRH receptor. Gonadorelin has been licensed as a medicine in several countries, mainly for diagnostic use and pulsed fertility therapy, though availability varies.

References

Formats available

Pen

Pre-filled injection pen for convenient subcutaneous use, prepared by a licensed compounding pharmacy.

Cartridge

Pre-filled cartridge for use with a compatible reusable injection pen.

Vial (injectable)

Lyophilised powder in a sterile vial, reconstituted before subcutaneous injection as directed by your pharmacy.

Storage and handling

Storage: Keep unopened lyophilised vials cool and dry, away from light. After reconstitution, refrigerate at 2-8C, protect from light and do not freeze. Keep pens and cartridges refrigerated at 2-8C and do not freeze. Follow the storage instructions on your pharmacy label.

Peptide Calculator

Specification

Property	Value
Sequence	pGlu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Molecular formula	C55H75N17O13
Molecular weight	approx. 1182 g/mol
Peptide length	10 amino acids
Formats	Pen, Cartridge, Vial (injectable)

Frequently asked questions

What does the research on gonadorelin show?

Clinical studies show that pulsed gonadorelin can stimulate LH and FSH release, and it has been studied in hypogonadotropic hypogonadism and ovulation induction. How it is given affects its action.

How is gonadorelin different from triptorelin?

Gonadorelin is identical to natural GnRH and is cleared within minutes. Triptorelin is a modified, longer-acting analogue. With continued use, triptorelin suppresses the hormone signals that gonadorelin is designed to support.

Are there side effects with Gonadorelin?

Side effects can occur. Your GP will review your health, medication and, where relevant, blood results before prescribing, and you should report anything unexpected.

Which formats are available and how should I store them?

Gonadorelin is available as: pen, cartridge, vial (injectable). Your GP will help you choose the most suitable format. Keep unopened lyophilised vials cool and dry, away from light. After reconstitution, refrigerate at 2-8C, protect from light and do not freeze. Keep pens and cartridges refrigerated at 2-8C and do not freeze. Follow the storage instructions on your pharmacy label.

How much Gonadorelin should I take?

Your dose is set by our licensed GP following a consultation, and printed on your pharmacy label.