HGH FRAGMENT 176-191
280.00 AED — In stock

HGH Fragment 176‑191 is a modified portion of the human growth hormone (HGH) molecule containing the last amino acids originally associated with fat metabolism and lipolytic signaling. Unlike full HGH, this fragment is engineered to focus on fat breakdown (lipolysis) and metabolic support without broad systemic growth or IGF‑1 elevation. It is used in research exploring body composition, energy balance, and adipose tissue metabolism. ⚗️ Product Features 🧪 Synthetic peptide fragment of HGH (176‑191) 🔥 Targets fat metabolism and lipolytic pathways ⚙️ Designed for enhanced fat‑burning research 📈 Supports metabolic balance and energy utilization investigation ✅ ≥98 % purity verified by HPLC 📄 Batch‑specific Certificates of Analysis (COAs) included 💧 Sterile, lyophilized peptide for research applications 🔬 Human‑Relevant Research Applications 🔥 Lipolysis & Fat Metabolism The C‑terminal region of HGH (amino acids 176–191) has been identified as the segment responsible for stimulating fat breakdown (lipolysis) and inhibiting fat formation (lipogenesis) in controlled research settings focused on metabolic pathways. This fragment has been used to study targeted fat metabolism and body‑composition modulation while bypassing many broader hormonal effects of full‑length HGH. 🔗 https://en.wikipedia.org/wiki/HGH_Fragment_176%E2%80%93191 — HGH Fragment 176–191 is a peptide fragment developed to isolate fat‑metabolizing activity from full HGH. 🧾 Mechanism Summary ⚡ Enhances lipolytic signaling linked to fat breakdown 🔥 Supports fat oxidation and energy utilization pathways 🚫 Minimizes effects on IGF‑1 and systemic growth compared with full HGH 📊 Used in metabolic and obesity‑related research on adipose tissue regulation 🔄 Reconstitution & Handling Guidance 1️⃣ Reconstitute using sterile bacteriostatic water2️⃣ Add appropriate volume per research protocol3️⃣ Gently swirl — do not shake4️⃣ Store reconstituted peptide at 4–10 °C5️⃣ Refrigerate unopened vials until use ❓ Frequently Asked Research Questions How does HGH Fragment 176‑191 support fat metabolism?It focuses on a portion of the HGH molecule linked to lipolysis and reduced fat cell formation while minimizing effects on growth and IGF‑1 pathways, making it useful for studies on metabolism and energy regulation.
What is HGH FRAGMENT 176-191?
HGH Fragment 176-191 is a short synthetic peptide matching the final section of human growth hormone, amino acids 176 to 191. Researchers identified this region as the part of the hormone most linked to its effects on fat metabolism.
The fragment does not appear to act on the main growth hormone receptor in the way the full hormone does. It is closely related to AOD-9604, a modified version of the same region that was developed for formal study. It is thought to influence fat breakdown in fat cells.
Also known as: hGH 176-191, Frag 176-191, GH fragment 176-191, Growth hormone fragment
What the research covers
Research on growth hormone fragments comes mostly from animal studies in the 1990s and early 2000s. In obese mice and rats, C-terminal growth hormone fragments have been studied for effects on fat breakdown and fat oxidation, without the effects on growth or blood sugar seen with full growth hormone. Most later human data relate to the modified form, AOD-9604, rather than the unmodified fragment. Early research suggests a possible role in fat metabolism, but human evidence is limited. HGH Fragment 176-191 is not approved as a medicine by the US FDA.
References
- Heffernan MA, Thorburn AW, Fam B. Increase of fat oxidation and weight loss in obese mice caused by chronic treatment with human growth hormone or a modified C-terminal fragment. International Journal of Obesity. 2001.
- Ng FM, Sun J, Sharma L. Metabolic studies of a synthetic lipolytic domain (AOD9604) of human growth hormone. Hormone Research. 2000.
Formats available
Pen
Pre-filled pen prepared by a licensed compounding pharmacy for subcutaneous use.
Vial (injectable)
Vial for subcutaneous injection, prepared by a licensed compounding pharmacy.
Storage and handling
Storage: Keep pens refrigerated at 2-8C and protect them from light. Lyophilised vials should be refrigerated at 2-8C after reconstitution, kept away from light and never frozen. Follow the storage instructions on your pharmacy label.
Specification
| Property | Value |
|---|---|
| Origin | C-terminal fragment of human growth hormone (residues 176-191) |
| Peptide length | 16 amino acids |
| Formats | Pen, Vial (injectable) |
Frequently asked questions
Is it the same as growth hormone?
No. It is a small piece of the growth hormone molecule. It does not appear to have the growth-related effects of the full hormone.
How does it compare with AOD-9604?
AOD-9604 is a modified version of the same region with an added tyrosine. Most formal animal and human research was carried out on AOD-9604.
What formats are available and how are they stored?
It is available as a pen or a vial. Keep pens in the fridge, and refrigerate vials after reconstitution, away from light. Follow the storage instructions on your pharmacy label.
Are there side effects?
Side effects can occur. Your GP will review your health, medication and, where relevant, blood results before prescribing, and you should report anything unexpected.
How much should I take?
Your dose is set by our licensed GP following a consultation, and printed on your pharmacy label.
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