Kisspeptin Pen

900.00 AED — In stock

Kisspeptin-5 is a biologically active peptide involved in the central regulation of human reproductive hormone signaling. It acts at the hypothalamic level to stimulate gonadotropin-releasing hormone (GnRH) secretion, initiating a downstream endocrine cascade that increases luteinizing hormone (LH) and follicle-stimulating hormone (FSH) release from the anterior pituitary gland. Through this upstream mechanism, Kisspeptin-5 plays a critical role in maintaining hypothalamic-pituitary-gonadal (HPG) axis function. It is widely studied in human reproductive endocrinology and fertility research for its ability to regulate gonadotropin secretion, ovulatory signaling, and overall hormonal balance. Key Features 🧫 cGMP manufactured in an FDA-registered facility📑 ≥98% purity verified by HPLC testing🧾 Batch-specific Certificates of Analysis (COAs) provided🖊️ Pre-filled sterile peptide pens for research use only Human-Relevant Research Applications 🔍 Central regulation of GnRH and gonadotropin release in humansHuman clinical research confirms that kisspeptin is a primary regulator of GnRH secretion, directly influencing LH and FSH release and establishing its essential role in reproductive hormone control.🔗 https://pubmed.ncbi.nlm.nih.gov/23256725/ 🔍 Role in fertility signaling and reproductive hormone balanceComprehensive human fertility research highlights kisspeptin’s involvement in ovulation, gonadotropin pulsatility, and HPG-axis regulation, supporting its relevance in fertility-focused research settings.🔗 https://link.springer.com/article/10.1186/s12958-022-00953-y Key Benefits 🌟 Regulates Reproductive Hormones – Stimulates GnRH release from the hypothalamus, driving LH and FSH production for healthy reproductive axis function. 🧠 Supports Fertility Research – Enhances gonadotropin signaling in both men and women, making it a key peptide in fertility optimization studies. ⚖️ Maintains Hormonal Balance – Helps modulate hypothalamic-pituitary-gonadal (HPG) axis activity, supporting endocrine homeostasis. 💡 Investigational Role in Ovulation Control – Explored in clinical studies for ovulation induction and reproductive hormone modulation. Mechanism Summary • Activates the KISS1 receptor (KISS1R) on hypothalamic neurons• Stimulates endogenous GnRH secretion• Indirectly increases pituitary LH and FSH release• Supports research into human fertility regulation, neuroendocrine signaling, and hormonal homeostasis

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What is Kisspeptin Pen?

Kisspeptins are natural peptides made from the KISS1 gene. Kisspeptin-10 is the shortest active form, made of the last ten amino acids of the longer kisspeptin-54. It was first studied as a metastasis suppressor, which is why it is also called metastin.

Kisspeptin acts on the KISS1 receptor (also called GPR54) on GnRH-producing nerve cells in the hypothalamus. This is thought to be a key upstream signal for GnRH release, which in turn prompts the pituitary to release LH and FSH. It sits one step above gonadorelin in the reproductive hormone pathway.

Also known as: Kisspeptin, KP-10, Metastin 45-54

What are peptides?

What the research covers

Kisspeptin has been studied in small human trials. In healthy men, kisspeptin-10 given by injection or infusion increased LH levels and LH pulse frequency. Other studies have looked at kisspeptin in women, in people with low reproductive hormone signalling, and as a trigger for egg maturation in IVF using kisspeptin-54. The research is mostly short-term and in small groups. Most human studies used injection or infusion rather than nasal delivery. Kisspeptin is not approved as a medicine in most countries.

References

George JT, Veldhuis JD, Roseweir AK, Newton CL, Faccenda E, Millar RP, Anderson RA. Kisspeptin-10 is a potent stimulator of LH and increases pulse frequency in men. The Journal of Clinical Endocrinology and Metabolism. 2011.

Formats available

Pen

Pre-filled injection pen for convenient subcutaneous use, prepared by a licensed compounding pharmacy.

Vial (injectable)

Lyophilised powder in a sterile vial, reconstituted before subcutaneous injection as directed by your pharmacy.

Nasal spray

Metered nasal spray, prepared by a licensed compounding pharmacy.

Storage and handling

Storage: Keep unopened lyophilised vials cool and dry, away from light. After reconstitution, refrigerate at 2-8C, protect from light and do not freeze. Keep pens and cartridges refrigerated at 2-8C and do not freeze. Refrigerate the nasal spray after opening unless your pharmacy label says otherwise. Follow the storage instructions on your pharmacy label.

Peptide Calculator

Specification

Property	Value
Sequence	Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Molecular formula	C63H83N17O14
Molecular weight	approx. 1302 g/mol
Peptide length	10 amino acids
Formats	Pen, Vial (injectable), Nasal spray

Frequently asked questions

What does the research on kisspeptin show?

Small human studies show kisspeptin-10 can raise LH and its pulse frequency in men. Research is early-stage and mostly short-term.

How is kisspeptin different from gonadorelin?

Kisspeptin acts higher up the pathway, on the nerve cells that release GnRH. Gonadorelin is GnRH itself and acts directly on the pituitary.

Are there side effects with Kisspeptin-10?

Side effects can occur. Your GP will review your health, medication and, where relevant, blood results before prescribing, and you should report anything unexpected.

Which formats are available and how should I store them?

Kisspeptin-10 is available as: pen, vial (injectable), nasal spray. Your GP will help you choose the most suitable format. Keep unopened lyophilised vials cool and dry, away from light. After reconstitution, refrigerate at 2-8C, protect from light and do not freeze. Keep pens and cartridges refrigerated at 2-8C and do not freeze. Refrigerate the nasal spray after opening unless your pharmacy label says otherwise. Follow the storage instructions on your pharmacy label.

How much Kisspeptin-10 should I take?

Your dose is set by our licensed GP following a consultation, and printed on your pharmacy label.