SEMAX

550.00 AED — In stock

Semax is a synthetic ACTH (4–10) analog developed for cognitive and neurological research. It has been studied in humans for effects on attention, memory, neural resilience, and neurotrophic signaling and has applications in stroke recovery and cognitive performance research. ⚗️ Product Features 🩺 Synthetic ACTH‑derived peptide (ACTH 4–10 analog) 🧪 Manufactured under strict peptide quality standards ✅ ≥98 % purity verified by HPLC 📄 Batch-specific Certificates of Analysis (COAs) included 💧 Sterile, lyophilized peptide for research applications 🔬 Human-Relevant Research Applications 🧠 Cognitive Function & Neuroplasticity Semax has been shown in clinical observations to support attention, short-term memory, and cognitive performancein humans, particularly under stress or fatigue conditions. It also influences BDNF levels, which are important for neuronal growth and synaptic plasticity.🔗 Clinical research overview and BDNF effects 🧩 Brain Network Activity & Rehabilitation Evidence from human studies indicates that Semax may enhance functional brain network activity, supporting neural resilience and recovery, including post-stroke rehabilitation.🔗 fMRI and clinical observations summary 🧾 Mechanism Summary 📈 Supports attention, memory, and working memory in human studies 🧩 Enhances functional brain network activity 🧬 Promotes BDNF-mediated neuronal growth and synaptic plasticity ⚙️ Modulates neural processes involved in learning and executive function 🔄 Reconstitution & Handling Guidance 1️⃣ Reconstitute using sterile bacteriostatic water2️⃣ Add appropriate volume per research protocol3️⃣ Gently swirl — do not shake4️⃣ Store reconstituted peptide at 4–10 °C5️⃣ Keep unopened vials refrigerated until use ❓ Frequently Asked Research Questions What cognitive functions has Semax been studied for in humans?Attention, short-term memory, EEG-linked cognitive activity, and brain network modulation. Does Semax influence neurotrophic factors in humans?Yes — increases in BDNF have been observed in human studies, supporting neuroplasticity and recovery.

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What is SEMAX?

Semax is a synthetic heptapeptide developed in Russia in the 1980s. It is built from a fragment of adrenocorticotropic hormone, ACTH(4-7), joined to a Pro-Gly-Pro sequence that helps it resist breakdown. Unlike ACTH itself, it is not thought to stimulate the adrenal glands.

Researchers think Semax may influence brain-derived neurotrophic factor (BDNF) and its receptor, which are involved in nerve-cell growth and plasticity. It may also affect dopamine and serotonin signalling. These mechanisms come mainly from animal studies and are not fully understood.

Also known as: ACTH(4-10) analogue, Met-Glu-His-Phe-Pro-Gly-Pro

What are peptides?

What the research covers

Semax has been studied mostly in cell and animal models. Rat studies have looked at memory, learning and the expression of BDNF in the hippocampus. Other animal work has examined nerve-cell protection after reduced blood flow to the brain. Some clinical studies in Russia have looked at Semax in stroke and other neurological conditions. These studies are generally small, and few have been replicated outside Russia, so the evidence remains early. Semax is registered as a medicine in Russia but is not approved as a medicine by the US FDA or the European Medicines Agency.

References

Dolotov OV, Karpenko EA, Inozemtseva LS, et al.. Semax, an analog of ACTH(4-10) with cognitive effects, regulates BDNF and trkB expression in the rat hippocampus. Brain Research. 2006.

Formats available

Pen

Pre-filled pen for subcutaneous use, prepared by a licensed compounding pharmacy.

Vial (injectable)

Lyophilised powder in a vial, reconstituted before use as directed by the pharmacy.

Nasal spray

Metered nasal spray for intranasal use.

Storage and handling

Storage: Store pens unopened in the fridge at 2-8C. Keep lyophilised vials cool and dry, and refrigerate at 2-8C after reconstitution. Refrigerate nasal sprays after opening unless the pharmacy label says otherwise. Protect all formats from light and do not freeze. Follow the storage instructions on your pharmacy label.

Peptide Calculator

Specification

Property	Value
Sequence	Met-Glu-His-Phe-Pro-Gly-Pro
Molecular formula	C37H51N9O10S
Molecular weight	approx. 813.9 g/mol
Peptide length	7 amino acids
Formats	Pen, Vial (injectable), Nasal spray

Frequently asked questions

How should I store Semax?

Keep pens in the fridge, refrigerate vials after reconstitution and refrigerate nasal sprays after opening unless the label says otherwise. Follow the storage instructions on your pharmacy label.

How is Semax different from Selank?

Semax is based on a fragment of ACTH and has mostly been studied for cognition and nerve-cell protection. Selank is based on tuftsin and has mostly been studied for anxiety and stress.

How much Semax should I use?

Your dose is set by our licensed GP following a consultation, and printed on your pharmacy label.

Are there side effects?

Side effects can occur. Your GP will review your health, medication and, where relevant, blood results before prescribing, and you should report anything unexpected.