Limitless Wellness

SS-31 Pen

900.00 AED — In stock

SS-31 Pen

SS‑31, also known as Elamipretide, is a mitochondria‑targeted tetrapeptide designed to protect and restore mitochondrial function — the energy‑producing core of human cells. By selectively binding to cardiolipin in the inner mitochondrial membrane, SS‑31 helps stabilize mitochondrial structure, reduce oxidative stress, and support efficient adenosine triphosphate (ATP) production — the primary energy currency of cells. These actions make SS‑31 a compelling investigational peptide in research on energy decline, aging‑related mitochondrial dysfunction, cardiovascular energetics, and conditions involving impaired cellular bioenergetics. Key Features 🔬 cGMP manufactured in an FDA‑registered facility📈 ≥98% purity confirmed by HPLC analysis📄 Batch‑specific Certificates of Analysis (COAs) included💉 Pre‑filled sterile peptide pens for research use only Human‑Relevant Research Applications ⚡ Improves mitochondrial energetics in human tissuesEx‑vivo studies using failing human heart tissue have shown that Elamipretide enhances mitochondrial respiratory supercomplex activity, improving oxygen flux and markers of electron transport efficiency in diseased human myocardium.🔗 https://pubmed.ncbi.nlm.nih.gov/PMC6488757/ 🔋 Elevates mitochondrial ATP production in older adultsA randomized trial in aging human skeletal muscle demonstrated that Elamipretide increases mitochondrial ATP production capacity (ATPmax) after a single infusion — the first pharmacologic evidence of acute improvement in human mitochondrial energetics in vivo.🔗 https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0253849 🧬 Clinically approved cardiolipin‑targeted mitochondrial therapyElamipretide (brand name FORZINITY™) has been granted accelerated approval by the U.S. FDA for the treatment of Barth syndrome — a rare mitochondrial disorder characterized by impaired cardiolipin metabolism and compromised energy production.🔗 https://pubmed.ncbi.nlm.nih.gov/32273339/ Key Benefits of SS‑31 ⚡ Supports Mitochondrial Energy Production – Enhances ATP generation by stabilizing the inner mitochondrial membrane and optimizing electron transport chain function. 🛡️ Reduces Oxidative Stress – Lowers mitochondrial reactive oxygen species (ROS), protecting cells from oxidative damage and age-related mitochondrial decline. 💪 Promotes Cellular Resilience – Maintains mitochondrial integrity under metabolic stress, supporting tissue energy capacity and organ function. ❤️ Investigational Cardiovascular Support – Clinically relevant in studies of cardiac bioenergetics, showing potential benefits in conditions with mitochondrial dysfunction. 🧬 Aging & Longevity Research – Studied for its translational potential in age-associated energy decline, neurodegeneration, and systemic mitochondrial dysfunction. Mechanism Summary • Selectively binds to cardiolipin in the inner mitochondrial membrane to support structural integrity and electron transport stability • Enhances mitochondrial respiration and ATP generation by improving coupling efficiency within the electron transport chain • Reduces pathological reactive oxygen species production linked to mitochondrial dysfunction in disease states • Supports translational research into aging‑related bioenergetic decline, muscle weakness syndromes, and mitochondrial myopathies

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What is SS-31 Pen?

SS-31, known by its drug name elamipretide, is a small synthetic peptide of four amino acids. It was developed by Hazel Szeto and Peter Schiller as one of the Szeto-Schiller (SS) peptides. Its sequence includes a D-arginine and a modified tyrosine (dimethyltyrosine).

SS-31 is designed to enter cells and concentrate in the inner mitochondrial membrane. There it is thought to bind cardiolipin, a lipid that supports the proteins of the energy-producing electron transport chain. By interacting with cardiolipin, it is thought to help stabilise mitochondrial structure and function.

Also known as: Elamipretide, Bendavia, MTP-131, Forzinity

What are peptides?

What the research covers

SS-31 has been studied in many animal models of heart, kidney, muscle and age-related mitochondrial dysfunction. In aged mice, early research suggests it may support mitochondrial function and exercise tolerance. Human research includes clinical trials in heart failure, primary mitochondrial myopathy and Barth syndrome, a rare inherited mitochondrial disorder. Results have been mixed across indications. In the TAZPOWER trial in Barth syndrome, the initial crossover phase did not meet its primary endpoints. A small long-term open-label extension reported improvements in some functional measures. In September 2025 the US FDA granted accelerated approval to elamipretide as Forzinity for Barth syndrome. It is not approved for ageing or general wellness.

References

  1. Thompson WR, Manuel R, Abbruscato A, et al.. Long-term efficacy and safety of elamipretide in patients with Barth syndrome: 168-week open-label extension results of TAZPOWER. Genetics in Medicine. 2024.
  2. Shirley M. Elamipretide: First Approval. Drugs. 2025.
  3. Szeto HH. First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics. British Journal of Pharmacology. 2014.

Formats available

Pen

Pre-filled pen for subcutaneous use, prescription only.

Vial (injectable)

Vial for subcutaneous injection, prepared by the pharmacy, prescription only.

Storage and handling

Storage: Vials are usually supplied lyophilised (freeze-dried). Once reconstituted, keep the vial refrigerated at 2-8°C, protected from light, and do not freeze. Pens should be kept refrigerated at 2-8°C and protected from light. Follow the storage instructions on your pharmacy label.

Peptide Calculator

Specification

PropertyValue
SequenceD-Arg-Dmt-Lys-Phe-NH2 (Dmt = 2',6'-dimethyltyrosine)
Molecular formulaC32H49N9O5
Molecular weightapprox. 639.8 g/mol
Peptide length4 amino acids
FormatsPen, Vial (injectable)

Frequently asked questions

Is SS-31 the same as Forzinity?

SS-31 is the research name for elamipretide. Forzinity is the brand of elamipretide approved by the US FDA in 2025 for Barth syndrome. Our product is a compounded preparation prescribed by our GP, not the branded medicine.

What does the research on SS-31 show?

SS-31 has been studied in many animal models of mitochondrial dysfunction and in human trials for rare mitochondrial disease and heart failure. Results in humans have been mixed. It is not approved for ageing.

How should I store SS-31 and what formats are available?

We supply SS-31 as a pen or vial. Keep both refrigerated at 2-8°C. Follow the storage instructions on your pharmacy label.

Are there side effects?

Side effects can occur. Your GP will review your health, medication and, where relevant, blood results before prescribing, and you should report anything unexpected. Injection site reactions were the most common effect reported in clinical trials.

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