THYMOSIN BETA-4 (Tβ4) - TB 500

300.00 AED — In stock

TB-500 is the synthetic fragment of Thymosin Beta-4 (Tβ4) — a naturally occurring peptide involved in cell migration, tissue repair, angiogenesis, and inflammation modulation across many biological systems. It’s widely used in research settings for regeneration and recovery studies. 🔍 Key Research-Supported Benefits 💪 Tissue Repair & RegenerationPromotes cell migration and wound healing by encouraging repair pathways in cell and tissue models.🔗 https://pubmed.ncbi.nlm.nih.gov/10469335/ — Tβ4 enhances wound healing, cell migration & angiogenesis in experimental models. 🩸 Angiogenesis & Vascular SupportDemonstrated to stimulate new blood vessel formation and endothelial cell activity — essential for nutrient delivery and regenerative research.🔗 https://pubmed.ncbi.nlm.nih.gov/14500546/ — Tβ4 has angiogenic activity, promoting endothelial cell migration and vessel sprouting. 🛡️ Cytoprotection & Cell SurvivalShown in research to improve survival and migration of endothelial progenitor cells under stress, a key component in regenerative studies.🔗 https://pubmed.ncbi.nlm.nih.gov/28440414/ — Tβ4 enhances cell viability, migration & capillary formation. 📈 Mechanism: Cell Migration & Cytoskeletal RegulationTB-500’s activity is tied to actin modulation, facilitating cellular movement crucial to tissue repair mechanisms.🔗 https://peptpedia.org/peptide/tb-500 — Research describes enhanced cell migration through cytoskeletal modulation. 🧠 Angiogenesis & Regenerative Pathways SummaryReview articles outline the mechanistic role of Thymosin Beta-4 peptides in wound healing and vascular regeneration.🔗 https://pubmed.ncbi.nlm.nih.gov/17632766/ — Review on Tβ4’s role in angiogenesis and tissue repair pathways. 📜 Product Features & Quality 🧪 cGMP manufactured in an FDA-registered facility ✅ ≥98% purity verified by HPLC 📄 Batch-specific Certificates of Analysis (COA) included 💉 Sterile, lyophilized peptide — for research use only 🔧 Reconstitution & Handling Guidance (Research Protocol) 1️⃣ Use sterile bacteriostatic water2️⃣ Add appropriate volume (e.g., 2–3 mL) based on your protocol3️⃣ Gently swirl to dissolve — do not shake/vortex4️⃣ Store reconstituted peptide at 4–10 °C5️⃣ Unopened vials remain stable until expiry when stored refrigerated 🧠 Frequently Asked Research Questions What is TB-500 mainly studied for?Primarily for its role in cell migration, tissue repair, angiogenesis and anti-inflammatory signaling in preclinical models. Does it have anti-inflammatory effects?Yes — preclinical studies and model analyses suggest modulation of inflammation and cytokine signaling as part of the healing process. (Though most references are in preclinical setups with rodents or cell lines.)

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What is THYMOSIN BETA-4 (Tβ4) - TB 500?

Thymosin beta-4 is a naturally occurring 43 amino acid protein found in most human cells. It binds actin, a structural protein that helps cells move and change shape. The name TB-500 is a commercial label rather than a scientific one. It is used both for synthetic full-length thymosin beta-4 and for a short fragment.

That fragment is often given as Ac-LKKTETQ, the actin-binding region of the full protein. Laboratory studies suggest thymosin beta-4 may influence cell migration, blood vessel formation and inflammation. These effects are being explored in tissue repair research.

Also known as: Thymosin Beta-4, Thymosin β4, Tβ4, TB4, TB500

What are peptides?

What the research covers

Thymosin beta-4 has been studied in cell and animal models of wound healing, heart injury, eye surface damage and muscle repair. Early research suggests it may support cell migration and new blood vessel formation in these models. Small human trials have tested full-length thymosin beta-4 in eye drops and wound gels, with mixed results. Most research uses full-length thymosin beta-4. Evidence for short fragments sold as TB-500 is much more limited. Neither thymosin beta-4 nor TB-500 is approved as a medicine by the US FDA.

References

Formats available

Pen

Pre-filled multi-dose injection pen prepared by a licensed compounding pharmacy.

Cartridge

Refill cartridge for a compatible reusable injection pen.

Vial (injectable)

Lyophilised (freeze-dried) powder for reconstitution, supplied with pharmacy instructions.

Nasal spray

Pharmacy-prepared nasal spray, an alternative to injection.

Storage and handling

Storage: Store pens and cartridges in the fridge at 2-8C and do not freeze. Keep lyophilised vials cool, dry and away from light; once reconstituted, refrigerate at 2-8C, protect from light and do not freeze. Refrigerate nasal sprays after opening unless the pharmacy label says otherwise. Follow the storage instructions on your pharmacy label.

Peptide Calculator

Specification

Property	Value
Sequence (full-length thymosin beta-4)	Ac-SDKPDMAEIEKFDKSKLKKTETQEKNPLPSKETIEQEKQAGES
Sequence (common TB-500 fragment)	Ac-LKKTETQ (thymosin beta-4 residues 17-23)
Peptide length	43 amino acids (full-length); 7 amino acids (fragment)
Formats	Pen, Cartridge, Vial (injectable), Nasal spray

Frequently asked questions

Which formats are available and how should I store TB-500?

TB-500 is available as a pre-filled pen, a cartridge for a reusable pen, a vial of freeze-dried powder or a nasal spray. Your GP will advise which format suits you. Store pens and cartridges in the fridge at 2-8C and do not freeze. Keep lyophilised vials cool, dry and away from light; once reconstituted, refrigerate at 2-8C, protect from light and do not freeze. Refrigerate nasal sprays after opening unless the pharmacy label says otherwise. Follow the storage instructions on your pharmacy label.

Is TB-500 the same as thymosin beta-4?

Not always. Thymosin beta-4 is the natural 43 amino acid protein. TB-500 is a trade name used for either a synthetic version of the full protein or a short fragment of it. Your pharmacy label states exactly what is supplied.

What does the research show?

Thymosin beta-4 has been studied in animal models of wound, heart and eye repair, and in small human trials of eye drops and wound gels. Evidence for TB-500 fragments specifically is limited. It should not be viewed as a proven treatment.

Are there side effects?

Side effects can occur. Your GP will review your health, medication and, where relevant, blood results before prescribing, and you should report anything unexpected.